10/02/2024
New preprint quantifying the propulsive forces that cells use to squeeze through small confinements
Check out Max’s paper using microfabrication, microscopy, and finite element modeling to understand how cells propel themselves through small confining spaces: preprint.
09/01/2024
Congrats to Yu Shi on his new position
Congratulations to Yu Shi on his new position as Assistant Professor of Physics at Western University in Ontario Canada! Check out his lab webpage here.
07/27/2024
New preprint on multiplexed super-resolution imaging in the nucleus
Check out Fariha’s paper using 3D super-resolution DNA PAINT to explore how a dozen different proteins and histone post translational marks are organized in the cell nucleus: preprint.
05/09/2024
Congrats to Dr. Daugird for defending his Ph.D.
News updates took a break during COVID, but now they’re back! Congrats and farewell to Tim Daugird who successfully defended his Ph.D. in Pharmacology and will be moving to a post doc in Computational Medicine at UNC. The microscope will miss you Tim!
10/15/2019
Support from the David and Lucile Packard Foundation
We’re honored to receive support from the David and Lucile Packard Foundation Fellowship in Science and Engineering. This award will provide flexible funding to develop a new generation of light sheet microscopes and to apply them to new areas of cell and developmental biology.
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10/01/2019
NIH New Innovator Award
Wesley Legant selected as one of the 2019 NIH New Innovators. This award will allow us to further develop our light sheet microscopes and apply them to new and exciting directions studying how gene expression patterns regulate cell fate decisions.
07/10/2019
3D Dynamics of mitotic spindle formation
Two recently published papers with the Gerlich and Kapoor labs using lattice light sheet to investigate mitotic spindle formation. Congrats to Ana and Melissa on the great work.
Augmin accumulation on long-lived microtubules drives amplification and kinetochore-directed growth
High-resolution imaging reveals how the spindle midzone impacts chromosome movement
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06/05/2019
Beckman Young Investigator Award
Wesley Legant named a 2019 Beckman Young Investigator. Arnold Beckman was a pioneer of scientific instruments. We’re honored by this award which will allow us to combine new machine learning algorithms together with lattice light sheet microscopy. Learn more about the Arnold Beckman and Mabel Beckman Foundation here.
06/01/2019
New Lab Member!
Very excited to have Tim Daugird join the group through the UNC Pharmacology graduate program. Welcome!
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04/18/2019
Searle Scholars Program
Wesley Legant named a 2019 Searle Scholar. We are extremely grateful for this funding to advance our work using light sheet microscopy to study the relationship between biophysical factors, nuclear architecture, and gene expression. Learn more about the Searle Scholars Program here.
11/7/2018
Art of Science and Innovation
Our work (as well as other UNC researchers) is featured in an exhibit at the North Carolina Museum of Art!
11/1/2018
Swiss Army Knife (SwaK) Microscope Build:
The optics rooms are complete, tables are installed, and we’re starting construction of our next-gen light sheet microscope! We’ll post photos of the build progress here.
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08/31/18
Improving Probes for Super-Resolution:
Regan’s news and views article is published in Nature Methods. Congrats!
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